開口一番
kai.kou.ichi.ban
Literally: open – mouth – one – [ordinal counter]
Alternately: The first thing out of someone’s mouth. The very first thing someone says when they start talking. Alternately, to start speaking suddenly and without warning.

The title of the first episode (appropriately enough) of the Durarara!! anime. It looks like every episode’s Japanese title is a yojijukugo, actually.